I am a 首席科学家 and a Medicinal Chemist within the early 心血管, 肾脏及代谢组. My focus is on synthetic chemistry where I, together with my team develop tools to make routes for our difficult-to-make compounds.
My area of expertise is C-H functionalisation, which is revolutionising how we design molecules within medicinal chemistry. By functionalising C-H bonds, we can save up to 20 steps in making molecules, which not only saves time but also has a positive sustainability impact, for example through using less reagent.
In 2020, I was honoured to be awarded Associate Professor at the Institution for Organic Chemistry, 斯德哥尔摩大学. I have a longstanding research collaboration with the university around C-H functionalisation in drug discovery and I look forward to this continuing in my new role.
I am passionate about working with and helping to develop early talent. I am inspired and proud by the commitment of the Postdocs and PhD students I supervise – past and present, and the impact their research has made in advancing medicinal chemistry.
I also have a global responsibility for AstraZeneca´s academic collaborations and strategic decisions in the field of organic chemistry.
In my daily work I get to engage with highly talented and motivated Postdocs and PhD students. 在一起, we have moved synthetic medicinal chemistry forward, all with the aim of getting new medicines to patients with unmet needs.
电流的作用
2020
2020
2019
特色的出版物
Redox-Neutral Photocatalytic C−H Carboxylation of Arenes and Styrenes with CO2.
König等2020. 化学细胞压机 2020. 出版链接: http://www.cell.com/chem/fulltext/S2451-9294(20)30432-0
Cobalt-catalysed C-H methylation for late stage drug diversification.
Friis年代, 约翰逊乔丹阿克曼·L. 化学性质, 2020
Selective C2 Functionalization of Histidine in Peptides.
房颤,吵着 约翰逊乔丹Gopalakrishnan R 等. 《澳门第一赌城在线娱乐》 国际教育,2019年
General Cyclopropane Assembly by Enantioselective Transfer of a Redox‐Active Carbene to Aliphatic Olefins.
Muratore M, Mendoza A, 约翰逊M J 等, 《澳门第一赌城在线娱乐》 Int Ed 2019, (front cover)
Relative Strength of Common Directing Groups in Palladium-Catalyzed Aromatic C-H Activation.
Tomberg A, Muratore M, 约翰逊乔丹 等. iScience (细胞),2019年
Direct Synthesis of N‑Alkyl Arylglycines by Organocatalytic Asymmetric Transfer Hydrogenation of N‑Alkyl Aryl Imino Esters.
Mazuela J, Antonsson T, Knerr L 等. 有机的信 2018